Endocrine Abstracts

Long-term sequels of pituitary radiotherapy include hypopituitarism, optic nerve atrophy, sensorineural hearing loss, neurocognitive impairment and second intracranial neoplasms, the meningioma being the most frequent. The cumulative incidence of second cerebral tumours within 20 years of the radiation is 2% and, unlike its primary forms, they show a more aggressive atypical histology, and the age of appearance varies depending on the latency time, which in its turn is proport...

Introduction: Hyponatremia is the most common electrolyte imbalance among hospitalised patients. Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is considered the most frequent etiology on patients with euvolemic hiponatremia. Conventional treatment includes water restriction and salt tablets with limited efficacy and very slow onset of action in certain patients.Material and methods: Systematic sampling of all SIADH patients treated wit...

Introduction: Syndrome of Inappropriate Antidiuretic (SIAD) is the most frequent cause of hyponatremia in parenteral nutrition (PN) patients. Moreover, SIAD may be caused by multiple etiologies (drugs; pulmonary, neurological or abdominal disorders; malignant disease; idiopathic…). Our objective was to evaluate the main etiologies of SIAD in patients receiving PN.Methods: Prospective, non-interventional, multicenter study in 19 Spanish hospitals. F...

Introduction: In patients receiving Parenteral Nutritcion (PN), hyponatremia is associated with increased in-hospital mortality. Our objective was to evaluate the influence of volemic classification (hypovolemia, euvolemia or hypervolemia) on in-hospital mortality in patients receiving PN presenting hyponatremia.Methods: Prospective, non-interventional, multicenter study in 19 Spanish hospitals. 543 non-critical patients receiving PN were recruited. Hypo...

Introduction / Background: Patients with advanced GEP-NENs often present with metabolic disorders and oncological treatments may increase malnutrition risk as well as alterations on body composition. Several studies have suggested that sarcopenia is independently associated with a worse prognosis in oncological patients. Sarcopenia predicts survival regardless of body weight; moreover, a reduced muscle mass is not only observed in cachectic individuals but also in overweight p...